How to check whether there is any problem with kidney function?

Kidney health has always been an issue that we need to pay attention to, so everyone still needs to be vigilant in normal times. Generally speaking, when checking kidney function, we can first make a detailed judgment based on the blood and urine test, and then a physical examination.

1. Blood urea nitrogen (BUN)

Reference value: Normal situation: diacetyl-oxime colorimetric method 1.8～6.8mmol/L, urease-natrium colorimetric method 3.2～6.1mmol/L.

Clinical significance: Increased: acute and chronic nephritis, severe pyelonephritis, acute and chronic renal dysfunction caused by various reasons, heart failure, shock, massive internal bleeding, burns, dehydration, adrenal cortex insufficiency, prostate hypertrophy, chronic urinary tract obstruction, etc.

2. Serum creatinine (Scr)

Reference value: Normal situation: Adult male 79.6～132.6μmol/L, female 70.7～106.1μmol/L, children 26.5～62.0μmol/L, whole blood 88.4～159.1μmol/L.

Clinical significance: Increase: renal failure, uremia, heart failure, gigantism, acromegaly, salicylate treatment, etc. Reduce: progressive muscular atrophy, leukemia, anemia, etc.

3. Blood urea

Reference value: Normal situation: 3.2～7.0mmol/L.

Clinical significance: Increased levels indicate acute and chronic nephritis, severe pyelonephritis, acute and chronic renal dysfunction caused by various reasons, heart failure, shock, burns, dehydration, massive internal bleeding, adrenal insufficiency, prostatic hypertrophy, chronic urinary tract obstruction, etc.

4. Serum uric acid

Reference value: Normal situation: Adult male 149～417μmol/L, female 89～357μmol/L; Male >60 years old 250～476μmol/L, female 190～434μmol/L.

Clinical significance: Increase: gout, acute and chronic leukemia, multiple myeloma, pernicious anemia, renal failure, liver failure, polycythemia, pregnancy reaction, strenuous activity and after high-fat meal, etc.

5. Urine creatinine (Cr)

Reference value: Normal situation: infants 88 ~ 176μmmol·kg-1/d; children 44 ~ 352μmol·kg-1/d; adults 7 ~ 8mmol/d.

Clinical significance: Increased in: hunger, fever, acute and chronic wasting diseases, after strenuous exercise, etc. Reduction: renal failure, muscular atrophy, anemia, leukemia, etc.