Symptoms and dangers of proteinuria

If proteinuria is confirmed, regular treatment should be carried out in a timely manner, and nutrition should be emphasized. The presence of proteinuria indicates that the kidneys have been damaged to varying degrees, which is also a relatively good standard. Long-term proteinuria indicates that the patient's condition is relatively serious and will seriously affect the health of the body. It is also relatively harmful and can easily lead to malnutrition, infection, and thrombosis, etc.

What are the dangers of long-term proteinuria?

It can cause the occurrence of uremia, and its hazards are diverse. Proteinuria is one of the symptoms of various kidney diseases. If it is not treated early, the consequences will be serious. Long-term and heavy proteinuria in nephrotic syndrome will lead to a large loss of plasma protein, causing hypoproteinemia. Proteinuria can cause damage to the glomeruli, renal tubules, etc., thereby causing renal fibrosis. Studies have confirmed that the occurrence of proteinuria is the first independent risk factor for uremia. The greatest harm of proteinuria is that it poisons the kidneys and causes uremia.

The hazards of long-term proteinuria are as follows: 1. Long-term hypoproteinemia can lead to malnutrition and slow growth and development in children; 2. The reduction of immunoglobulins causes low immunity of the body and is prone to infection; 3. Insufficient endocrine binding protein can induce endocrine disorders (low T3 syndrome, etc.); 4. The loss of metal binding protein can lead to trace element (iron, copper, zinc, etc.) deficiency; 6. Hyperlipidemia increases blood viscosity, promotes the occurrence of thrombosis and embolism complications, and will also increase cardiovascular system complications, and may promote the occurrence of glomerular sclerosis and simple tubular lesions, and promote the chronic progression of renal disease.

1. Functional proteinuria Functional proteinuria is a mild (24-hour urine protein quantity generally does not exceed 0.5-1 gram), temporary proteinuria. The proteinuria disappears rapidly after the cause is removed. It often occurs in young and middle-aged people, and can be seen after mental stress, severe cold or heat, long-distance marches, strenuous physical labor, congestive heart failure, and eating a high-protein diet. 2. Postural proteinuria: There is no protein in the urine in the morning, but proteinuria gradually appears after getting up and moving around. The protein content in the urine increases when standing, walking or strengthening the lordotic posture for a long time. The protein content in the urine decreases or disappears after lying down for 1 hour. It often occurs in young people or adults with a slender body shape. Recurrent postural proteinuria requires the exclusion of renal disease, such as the nutcracker phenomenon (also called left renal vein compression syndrome, which is caused by compression of the left renal vein by the aorta and superior mesenteric artery). 3. Pathological proteinuria: Proteinuria persists, the protein content in the urine is high, and routine urine examination often shows hematuria, leukocyturia and tubular urine. It may also be accompanied by other manifestations of kidney disease, such as hypertension, edema, etc. Pathological proteinuria is mainly seen in various glomerular and tubulointerstitial diseases, hereditary kidney diseases, renal vascular diseases and other kidney diseases.