Clinical application of fat-soluble vitamin 2

Fat-soluble vitamin 2 is a relatively common injectable vitamin. It is mainly used for enteral malnutrition and can meet the physiological needs of vitamin deficiency. It is commonly used in clinical applications, such as vitamin A deficiency, vitamin D deficiency, or vitamin E deficiency, etc. When using fat-soluble vitamin 2, you should also understand some precautions to avoid adverse reactions.

Clinical application 1. Vitamin A (1) Vitamin A deficiency: Oral administration, 100,000 units per day for adults, change to 50,000 units per day after 3 days for 2 weeks, then 10,000 to 20,000 units per day for another 2 months. (2) Mild vitamin A deficiency: 30,000 to 50,000 units per day, taken orally in 2 to 3 doses. Reduce the dosage after symptoms improve. 2. Vitamin D treatment of vitamin D deficiency: Adults 0.025-0.05 mg (1000-2000 IU) per day, then reduced to 0.01 mg (400 IU) per day; children 0.025-0.1 mg (1000-4000 IU) per day, then reduced to 0.01 mg (400 IU) per day. Vitamin D-dependent rickets: Adults: 0.25-1.5 mg (10,000-60,000 IU) per day, maximum daily dose: 12.5 mg (500,000 IU) per day; children: 0.075-0.25 mg (3,000-10,000 IU) per day, maximum daily dose: 1.25 mg (50,000 IU) per day.

Adverse Reactions 1. Long-term use of large doses of vitamin A can cause hypervitaminosis A, or even acute or chronic poisoning, with the highest incidence in infants aged 6 months to 3 years. Symptoms include loss of appetite, itchy skin, dry hair, hair loss, chapped lips, irritability, bone pain, fractures, and increased intracranial pressure (headache, vomiting, wide and bulging anterior fontanelle). It may disappear after 1 to 2 weeks of stopping the medication. Overdose can cause poisoning. 2. Vitamin D ① Cardiovascular system: arrhythmia and hypertension may be seen; ② Psychoneural system: convulsions and occasional mental abnormalities may occur; ③ Gastrointestinal tract: nausea, vomiting, dry mouth, metallic taste in the mouth, lack of appetite, diarrhea, severe abdominal pain (sometimes misdiagnosed as pancreatitis), constipation, and weight loss may be seen; ④ Urogenital system: nocturnal polyuria and turbid urine may occur; ⑤ Musculoskeletal system: myalgia and bone pain may occur; ⑥ Eyes: increased sensitivity of the eyes to light stimulation may occur; ⑦ Skin: itchy skin may occur; ⑧ Others: fatigue and weakness may occur.