Symptoms of lymphadenopathy

Lymphatic lesions are particularly harmful to patients. They may be caused by tumors. Patients often have fever and weight loss, and their weight may decrease by more than 10%. They often experience night sweats, loss of appetite, fatigue, itchy skin, etc., which can lead to poor immunity. Some systemic symptoms are also relatively obvious, posing a great risk to the patient's life safety.

Symptoms of lymphadenopathy

1. The fever pattern is mostly irregular, which may be continuous high fever or intermittent low fever. A few have periodic fever, which is seen in about 1/6 of Hodgkin's disease patients. About 30% to 50% of patients with Hodgkin's disease have early fever, but patients with non-Hodgkin's lymphoma generally only have fever when the lesions are more extensive. Profuse sweating when the fever subsides may be a characteristic of this disease.

2. Skin itching is a more specific manifestation of Hodgkin's disease. Focal pruritus occurs in the area of lymphatic drainage of the lesion, while generalized pruritus mostly occurs in cases with lesions in the mediastinum or abdomen. 3. Alcohol pain: About 17% to 20% of Hodgkin's disease patients experience pain in the lesion area 20 minutes after drinking. Its symptoms may appear earlier than other symptoms and X-ray manifestations, and have certain diagnostic significance. When the lesion is relieved, the alcohol pain disappears immediately, but reappears when it relapses. The mechanism of alcohol pain is unclear.

4. Symptoms of extranodal lesions (1) Gastrointestinal symptoms include loss of appetite, abdominal pain, diarrhea, abdominal mass, intestinal obstruction and bleeding. (2) Invasion of the hepatobiliary and liver parenchyma can cause pain in the liver area. (3) Skeletal clinical manifestations include local bone pain and secondary nerve compression symptoms. (4) Common nonspecific skin damages include pruritus and prurigo. Pruritus is more common in Hodgkin's disease (accounting for 85%). (5) Tonsillar and oral, nasal, and pharyngeal lymphomas that invade the mouth, nose, and pharynx may result in clinical symptoms such as dysphagia, nasal congestion, and epistaxis. (6) Other lymphomas may also infiltrate the pancreas and cause malabsorption syndrome.

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