New drugs for schizophrenia

New drugs for schizophrenia

Everyone must have heard of mental illness, which is mostly manifested as psychological depression, autism or extreme attitudes. Mental illness includes schizophrenia. Schizophrenia is a disease in which multiple personalities appear, and these personalities do not exist. The personalities themselves are unaware of what they do. Schizophrenia can be treated with some drugs, so what are the new drugs for schizophrenia?

Schizophrenia is a group of severe mental illnesses with unknown etiology. They usually develop slowly or subacutely in young and middle-aged people. Clinically, they often manifest as a syndrome with varying symptoms, involving multiple disorders in perception, thinking, emotion, and behavior, as well as incoordination of mental activities. Patients are generally conscious and have basically normal intelligence, but some patients will experience cognitive impairment during the course of the disease. The course of the disease is generally protracted, with repeated attacks, aggravation or deterioration. Some patients eventually decline and become mentally disabled, but some patients can remain cured or almost cured after treatment.

Schizophrenia is a clinical syndrome consisting of a group of symptoms and is a multifactorial disease. Although the cause of the disease is still unclear, it is generally acknowledged that the individual's psychological susceptibility and the adverse factors of the external social environment play a role in the occurrence and development of the disease. Both susceptibility and external adverse factors may lead to the occurrence of the disease through the combined effects of internal biological factors. The factors that cause the disease in different patients may be more important in one aspect.

Antipsychotic drugs are divided into two types: typical antipsychotics (traditional antipsychotics) and atypical antipsychotics (non-traditional antipsychotics). Typical antipsychotics

Typical antipsychotics, represented by chlorpromazine, are mainly used to treat schizophrenia and mania; atypical antipsychotics Traditional (or typical) antipsychotics are mostly simple dopamine D2 receptor blockers, and the current focus of antipsychotic drug research and development is on atypical antipsychotics.

Given that antipsychotics have many pharmacological effects, when many antipsychotics have similar effects, adverse drug reactions become the determining factor in whether to choose to use a certain drug. The occurrence of adverse reactions is related to different diseases, types of drugs, medication methods and dosages, and combined medications. The use of antipsychotic drugs should be avoided as much as possible in combination, and the principle of single medication should be advocated. When combining medications, attention should be paid to drug interactions, especially the effects of drug metabolism and liver enzymes.

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