Can I still drink expired Chinese medicine?

Can I still take granular medicine one year after its expiration? For medicines that have expired, whether it is one day or one month past their expiration date, there is no way to ensure that they are not ineffective or moldy. So, can granular medicines still be taken if they are one year past their expiration date? Let’s take a look with the editor.

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1. Can I still take the granular medicine if it is one year past its expiration date?

2. General standards for the expiration date of granular drugs

3. Determination of Chinese medicine granules

Can I still take the granular medicine after it expires for 1 year?

1. Can I still take the granular medicine if it is one year past its expiration date?

As for whether expired medicines are valid, or even whether they will become moldy and affect physical and mental health. First of all, the deterioration of drugs is a slow process, and this process is different for different drugs. However, for drugs that have expired, whether it is one day or one month, it is impossible to ensure whether they are invalid or moldy, because this has exceeded the deadline for the data obtained by the manufacturer's reliability test and long-term sample observation test. In addition, the speed at which drugs change is affected by factors such as drug composition, storage environment, or whether they have been used in the market. Once any problems arise from the use of expired drugs, the manufacturer will no longer bear any responsibility. To sum up, expired drugs cannot be guaranteed in terms of quality, efficacy and even laws and regulations, so their use is not recommended.

2. Expiration date of granular drugs

The shelf life of a drug refers to the period during which its quality can be maintained under certain storage standards. The expiration date refers to the time when the drug cannot be used again if its quality does not meet the nationally recognized product quality standards and regulations under the required storage conditions. Domestic drugs are listed in the order of year-month-day, and the validity period is generally expressed as XX year XX month, or in numbers, which means that the drug can be used until the end of the last month of the validity period. The expiry date of imported medicines. Imported drugs often use an expiry date to indicate their expiration date, or a use before to indicate their validity period.

3. Measurement of the expiration date of particulate drugs

Adjust the temperature of the very constant temperature bath to 40 ± 0.2 °C. Use a measuring cylinder to take 5b250l of about 0.4% streptomycin sulfate aqueous solution and place it in a 100ml ground-mouth bottle, and place the conical bottle in a constant temperature bath at 40℃. Use a precision pipette to draw 0.5ml of 2.b250ol/L sodium hydroxide solution and quickly add it to the streptomycin sulfate aqueous solution. When the alkali amount is added to half, start the timer and start recording the time. Take 5 dry 5b250l ground-mouth conical flasks, number them, and accurately add 2b250l 0.5 mol/L 0.5% iron test reagent to each flask with a pipette, and then add 5 drops of 1.12-1.18 mol/L sulfuric acid solution. Every 10 minutes, accurately take 5 ml of the reaction solution into the conical flask, shake it until it turns dark purple, leave it for 5 minutes, and then measure the extinction value Et with a 722 photometer at a light wavelength of 520nm, and record the experimental data.

General standards for the expiration date of granular drugs

1. The shelf life of a drug is usually determined by the results of long-term sample reliability tests on small-scale or larger products. If the long-term sample retention safety test time is too short to determine its shelf life, if the influencing factor test and accelerated test data of the chemical raw material drug or its Chinese medicine preparation show that the drug is relatively stable, and the Chinese medicine preparation is also very simple, its appropriate shelf life can be determined by referring to the safety test results of its clinical test sample.

2. If the long-term sample retention reliability test time is short and its validity period cannot be determined, and the influencing factor test and accelerated test data of the chemical raw material drug or its Chinese medicine preparation show that the drug is not stable enough, that is, its small-scale trial cannot reflect the reliability of small-scale or above trial scale, the establishment of this validity period must be based on the test results of small-scale or above trial scale samples.

3. For the types of injections that are immediately reported for production, if the long-term sample retention reliability test time is less than one year, under the premise that the influencing factor test and accelerated test results are stable, the pending validity period cannot exceed one year. For those who apply to extend the validity period, the applicant company shall provide the results of long-term sample retention reliability tests that are applicable to the validity period of its application.