How to cure fungal vaginitis

How to cure fungal vaginitis

Vaginitis is a very common type of gynecological inflammation. Many women suffer from it, and women of all ages may suffer from it. Vaginitis has a lot of impact on the lives of women, especially candidal vaginitis, which is the most common type of vaginitis. It is also easy to recur, causing great pain to women. Everyone wants to know how to cure candidal vaginitis.

Vaginitis should be very familiar to female friends, especially married women, who will suffer from vaginitis. Fungal vaginitis is also a common one. Women with this disease will experience symptoms of vaginal itching, which affects their life and work. So how to cure fungal vaginitis?

Causes of vaginal candidiasis

The main pathogen of candidal vaginitis is Candida albicans. Candida albicans is a conditional pathogen that parasitizes in the vagina of about 10% of non-pregnant women and 30% of pregnant women, but does not cause symptoms. The vaginal pH of a Candida infection is between 4.0 and 4.7, usually <4.5. When the glycogen in the vagina increases, the acidity increases, and the local cellular immunity decreases, it is suitable for Candida to multiply and cause inflammation. Therefore, it is more common in pregnant women, diabetics, and those receiving large amounts of estrogen treatment. Long-term use of broad-spectrum antibiotics can cause an imbalance in the normal vaginal flora. Wearing tight nylon pants can increase the local humidity and temperature of the perineum, which is also conducive to the reproduction of Candida albicans. A small number of patients can also become ill through direct transmission through sexual intercourse or contact with the infected person's clothing.

The glycogen content in the vaginal epithelium of pregnant women increases and the vaginal acidity increases, which provides favorable conditions for the reproduction of Candida albicans. Therefore, the incidence of Candida albicans vaginitis in pregnant women is significantly higher than that in non-pregnant women. In recent years, some studies have shown that Candida albicans, as an allergen, can induce the body to produce a specific immune response.

Compared with healthy women, patients with recurrent vaginal candidiasis (RVC) have an increased proportion of Candida albicans-specific T cell clones produced by damaged vaginal mucosa and peripheral blood monocytes, and a decrease in the production of interferon-γ by monocytes after Candida albicans stimulation, suggesting that patients with recurrent vaginal candidiasis may have some degree of T cell response defect.

In addition, long-term use of antibiotics changes the mutual restraint relationship between microorganisms in the vagina; corticosteroids or immunodeficiency syndrome reduce the body's resistance; wearing tight synthetic underwear and obesity can increase the local temperature and humidity of the perineum, making it easy for Candida to multiply and cause infection.

Treatment of vaginal candidiasis

prevention:

1. Rationally use broad-spectrum antibiotics, and actively treat diabetes.

2. Candida can exist in the human oral, intestinal and vaginal mucosa, so you should be careful about cross-infection.

treat:

1. Eliminate the causes

Pay attention to personal hygiene, actively treat diabetes, stop using broad-spectrum antibiotics or corticosteroids, and pregnant women should pay attention to hygiene during pregnancy and prevent cross infection.

(II) Topical medication

Change the vaginal acidity and alkalinity. Flushing the vagina with 2% to 4% sodium bicarbonate solution can change the vaginal acidity and alkalinity, creating an environment that is not conducive to the growth of Candida albicans, which is conducive to improving the efficacy, and then place the medicine locally. Commonly used vaginal medications include:

l. Nystatin suppositories or tablets

Generally, 100,000 units are placed in the vagina once a night, and a course of treatment is 7 to 10 days. For example, Micodin vaginal effervescent tablets contain 100,000 units of nystatin per tablet.

2. Clotrimazole suppositories or tablets

Take 1 capsule (150 mg) or 1 tablet (250 mg) every night for 7 consecutive days, or 500 mg. It can be used for 1-3 days depending on the condition.

3. Miconazole suppository

Take 1 tablet (200 mg) every night for 7 consecutive days, or 400 mg for 3 consecutive days.

4. Gentian violet solution: Apply 1% gentian violet solution to the vagina 3-4 times a week for two weeks.

(III) Systemic medication

If local medications are ineffective, cannot be tolerated, unmarried women are unwilling to use local medications, or the condition is stubborn, the following drugs can be used: itraconazole 200 mg each time, orally once a day for 3 to 5 days, or 400 mg a day, orally in 2 divided doses; fluconazole 150 mg once; ketoconazole 200-400 mg each time, orally once a day for 5 days. After taking the medicine, you should pay attention to testing your liver function. It is forbidden for people with a history of hepatitis or pregnant women to use it.

(IV) Treatment of stubborn cases

Patients who have not been cured for a long time should pay attention to whether they have diabetes or Trichomonas vaginitis. If necessary, in addition to local treatment, oral nystatin tablets can be taken to prevent cross-infection of intestinal Candida. You can also use itraconazole 200 mg each time, orally once a day, for 3 to 5 times in a row; or fluconazole, or ketoconazole, 400 mg per day, taken at once (at the same time as a meal), 5 days as a course of treatment. It is forbidden for pregnant women and patients with acute and chronic hepatitis.

5. Treatment of recurrent cases

Candidal vaginitis is prone to relapse before menstruation after treatment, so the leucorrhea should be checked before menstruation. For recurrent cases, attention should be paid to eliminating the predisposing factors; sexual partners should also be examined and treated for Candida albicans; antifungal agents should be used mainly systemically, with increased drug dosage and duration of application. Usually the therapeutic dose is used for 10 to 14 days, followed by the preventive dose. The preventive dosage of commonly used drugs is: fluconazole 150 mg each time, once a week, for 6 months; itraconazole 100 mg each time, twice a day, for 7 consecutive days per month, for 6 months; ketoconazole 400 mg per day, for up to 6 consecutive months. Regularly monitor the efficacy and side effects of medication during use.

6. Treatment during pregnancy

To avoid infection of newborns, local treatment should be used, and drugs with little effect on pregnant women and fetuses should be selected. Miconazole nitrate or nystatin suppositories can be used. Systemic medication is prohibited.

Caused by Candida albicans infection. Candida albicans is a conditionally pathogenic bacterium. About 10% of non-pregnant women and 30% of pregnant women have this bacterium parasitic in their vagina without showing any symptoms. When the body's resistance is reduced, the glycogen in the vagina increases, and the acidity rises, it is suitable for its reproduction and causes inflammation. Therefore, it is more common in pregnant women, diabetics and patients treated with high doses of estrogen. Patients receiving long-term antibiotic therapy may experience a loss of mutual control of vaginal microorganisms, leading to the growth of Candida albicans. Other factors such as vitamin deficiency, chronic wasting diseases, wearing tight synthetic underwear, and obesity can increase the local temperature and humidity of the perineum and are all prone to the disease.

When candidal vaginitis occurs, the symptoms of itching will be obvious, and you will want to scratch it irresistibly. However, if you are outside, you still need to pay attention to your image, which makes women very uncomfortable. Moreover, the incidence of vaginitis is very high now. Almost all women who have sex have vaginitis. Everyone should actively learn how to cure candidal vaginitis and get rid of the troubles of the disease in time.

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