What are the effects and functions of Zuojin Pills?

Zuojin Pills is a Chinese patent medicine. Its main ingredients are Coptis chinensis and Evodia rutaecarpa. It can clear away heat and treat vomiting. However, many people do not know Zuojin Pills and do not know what medicine it is. When seeing a doctor in the hospital, they take whatever medicine the doctor prescribes. Many patients do not pay attention to medicines. In fact, it is good to understand the efficacy and effects of the medicine before taking it. Patients can clearly know the purpose of taking it. So what are the main effects and effects of Zuojin Pills?

Function and indications:

Clears away liver fire, reduces adverse reactions and stops vomiting. Liver fire attacking the stomach syndrome. Pain in the ribs, noisy and acid-regurgitating stomach, vomiting with a loud gurgling sound, red tongue with yellow coating, and stringy and rapid pulse. (This prescription is often used for gastritis, esophagitis, gastric ulcer and other conditions caused by liver fire attacking the stomach.)

1. Effects of Zuojin Pills on the Digestive System

Zuojin Pills at doses of 4 g/kg and 6 g/kg could significantly inhibit gastric emptying in mice (P<0.05); doses of 2 g/kg, 4 g/kg, and 6 g/kg could significantly inhibit small intestinal propulsion in mice (P<0.01). The inhibitory effect of a dose of 2 g/kg was similar to that of 2.5 mg/kg of atropine, and this effect was alleviated after the addition of costus root. It also has obvious anti-ulcer effect. The water extract of Zuojin Pill (dose of 6.7g crude drug/kg body weight) can promote the healing of experimental gastric lesser curvature ulcer in rats. After 5 days of treatment, the healing rate reached 93.33%, which was significantly higher than that of the ranitidine group (effectiveness 81.25%) and the normal saline group (effectiveness 47.06%).

2. Antibacterial effect of Zuojin Pills

The plate punching method was used, and the Zuojin Pill solution was added and cultured for 24 hours. Zuojin Pill had a strong antibacterial effect on Staphylococcus aureus, Vibrio cholerae, and Group B Streptococcus, and a slightly weaker antibacterial effect on Shigella dysenteriae, Escherichia coli, and Salmonella typhi.

3. Anti-inflammatory and analgesic effects

The hot plate method was used to gavage mice with 6g/(kg.d) of Zuojin Pills for 5 consecutive days, which could increase the analgesic threshold of mice, which was significantly different from that of the normal saline group; the writhing method was used to gavage mice with 6g/(kg.d) of Zuojin Pills for 5 consecutive days, which had a significant inhibitory effect on the writhing reaction caused by 0.5% acetic acid, which was significantly different from that of the normal saline group. It can also fight inflammation. Gavage of 1g/(kg.d) Zuojin Pill to rats for 6 consecutive days can inhibit the proliferation of cotton ball granulation tissue, which is significantly different from that of the normal saline group.

The above content introduces the effects and functions of Zuojin Pills. Patients should pay attention when taking the medicine. The diet must be light during the medication period, and spicy and greasy foods cannot be eaten. In addition, the body symptoms must be observed after taking the medicine. If there are allergic reactions or severe side effects, the medication must be stopped to prevent accidents after the patient uses the medicine. When the patient uses the medicine for three days or more and finds that the condition has not improved, he must go to the hospital for examination and treatment.