Pufferfish may seem like a relatively docile aquatic creature, but little do people know that they contain a certain amount of toxins in their bodies. Medical research has found that if these toxins are used correctly, they can have amazing effects. They can treat nasopharyngeal cancer, esophageal cancer, gastric cancer, etc., and can also be used for pain relief. There are many types of pufferfish. The toxicity of pufferfish is relatively higher when they are longer, and the toxicity of their tissues and organs also varies. The order of pufferfish toxins from largest to smallest is: ovary, liver, spleen, blood tendons, gills, skin, and testis. Winter and spring are the spawning seasons for pufferfish. At this time, the pufferfish The meat tastes the best, but also contains the most toxins. With the advancement of science, the dreaded tetrodotoxin has entered the halls of pharmacy and is playing an increasingly important role in the treatment of human diseases. Tetrodotoxin can be used medically to treat cancer. "New Life Oil" is an anti-cancer drug extracted from pufferfish liver. It is used to treat nasopharyngeal cancer, esophageal cancer, gastric cancer, and colon cancer, with very good results. Pufferfish can be used for pain relief. Tetrodotoxin preparations have a good analgesic effect on cancer pain, pain after surgery, and pain caused by gastric ulcers. The advantage of using pufferfish is that the dosage is extremely small (only 3 micrograms), the pain relief lasts for a long time, and it is not addictive. Acupuncture injection, in particular, has a fast-acting and obvious effect, and can be used as a good substitute for addictive analgesics morphine and pethidine. Pufferfish toxin can also relieve asthma, spasms and itching. Tetrodotoxin can treat asthma and whooping cough. It is particularly effective in treating gastrointestinal spasms and tetanus spasms. Tetrodotoxin has a strong killing effect on bacteria. The toxin extracted from pufferfish testes has inhibitory effects on Shigella dysenteriae, Salmonella typhi, Staphylococcus aureus, Streptococcus aureus, and Vibrio cholerae, and can also prevent and treat influenza. Currently, in the international market, the price of pufferfish toxin crystals per gram has reached as high as 170,000 US dollars. Now, tetrodotoxin can be synthesized artificially. Recently, Canadian scientists have developed a new pain-relieving drug using pufferfish toxin. This new special analgesic can effectively relieve pain in cancer patients. Currently, this project has completed phase I and phase II clinical trials. In clinical trials, doctors injected patients with the drug twice a day, a few micrograms each time, for four consecutive days. After the third day of medication, the patient's pain began to ease. As a result, nearly 70% of patients experienced relief from their pain. The researchers also found that the pain-relieving effects lasted even after the last injection was stopped. In some cases, the pain relief can last up to 15 days. Edward Sellers, a professor of pharmacology at the University of Toronto in Canada, said the drug can block pain-related nerve signals sent to the brain and its analgesic effect is 3,000 times stronger than morphine. |
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