What is herpes? Three major causes of herpes

Herpes is a skin disease and has different classifications, but no matter what type it is, you must pay attention to active treatment and understand the causes of herpes, such as basal cell liquefaction and basement membrane lesions or acantholysis, which may cause herpes.

Herpes refers to small yellow-white or translucent blisters that appear on the skin surface. They often appear in patches and are filled with fluid. Smallpox, chickenpox, etc. have this symptom; the second refers to a skin disease, the pathogen is a virus, which often occurs on the upper lip or face. The symptoms are local itching first, and then the appearance of blister-like protrusions containing clear liquid, which is slightly painful, and scabs and heal themselves after one or two weeks. Herpes is divided into genital herpes, herpes simplex, and herpes zoster.

1. Spinolysis:

Due to the degeneration of intercellular bridges (desmosomes and tension filaments, etc.) in the epidermis, the cells lose their tight connection and become loose, thus forming cracks, blisters or blisters in the epidermis. Acantholysis can be caused by autoimmune factors, such as pemphigus. Acantholysis caused by genetic factors is seen in chronic familial benign eczema and keratosis follicularis.

2. Basal cell liquefaction and basement membrane lesions:

Basal cell liquefaction refers to the cavitation or fragmentation of epidermal basal cells. In severe cases, the basal cell layer disappears, and the spinous cells are in direct contact with the dermis. Immunity, genetics, and drug allergies are often the causes of basal cell liquefaction, which is seen in hereditary epidermolysis carcinoma, systemic lupus erythematosus, dermatomyositis, erythema multiforme, drug eruption, and ulcerative lichen planus. Basement membrane lesions refer to the deposition of autoantibodies or congenital pathological defects in the basement membrane, which are caused by autoimmunity and genetics. Watery dysentery diseases caused by basement membrane lesions include pemphigoid herpes, herpes gestationis, cicatricial pemphigoid, dermatitis herpetiformis, linear epidermolysis bullosa, acquired epidermolysis carcinomatosa, congenital epidermolysis bullosa, and incontinence pigmenti.

3. Balloon degeneration and reticular degeneration:

Due to intracellular edema, the volume of epidermal cells increases, forming a balloon shape. The cells swell and rupture, and the adjacent remaining cell membranes connect into multiple reticular septa, finally forming multilocular ulcers, which are more common in viral infectious skin diseases.