How to treat and improve gonococcal infection

Gonococcal infection is one of the common sexually transmitted diseases. This infection is also called gonorrhea and is mainly transmitted through sexual intercourse. Many people do not know how to treat gonococcal infection. Gonococcal infection is generally treated with medication, and sexual intercourse should also be stopped.

(1) Gonorrhea resistance:

According to the data of gonococcal resistance monitoring in my country in recent years, chromosomal resistance of gonococcal isolates to penicillin and tetracycline is relatively common in my country, and has been detected in many cities and regions (PPNG). Plasmid-mediated TRNG is also on the rise. Penicillin and tetracycline are currently no longer recommended drugs for the treatment of gonorrhea. In addition, quinolone-resistant gonococci have appeared in my country, and the rate of resistant strains has increased year by year. In many areas, the rate of quinolone-resistant gonococci is as high as over 80%. In these areas, this type of drug should not be used to treat gonorrhea. In areas where quinolone resistance is unclear, when ciprofloxacin or ofloxacin is used in patients, close follow-up is required to observe the efficacy or adjust the treatment plan in time to prevent treatment failure.

(2) Mixed infection:

Urogenital gonococcal infection is often combined with Chlamydia trachomatis infection (about 20% in men and about 40% in women). Therefore, it is recommended that adult gonorrhea patients undergo routine chlamydia screening or use drugs to treat chlamydia at the same time, such as doxycycline 100 mg/time, 2 times/day, orally for 10 days, or azithromycin 1g, taken all at once.

(3) Treatment of sexual partners:

Gonorrhea is a curable sexually transmitted disease, but the human body has no effective specific immunity to gonococcal infection, and one of its characteristics is easy repeated infection. Failure to receive treatment for sexual partners is often an important cause of recurrence or reinfection of gonorrhea. Therefore, the sexual partners of all patients diagnosed with gonococcal infection should be tracked, and the sexual partners of male patients with symptomatic urethral infection who have had contact within the past 2 weeks should be examined and treated. The sexual partners of patients with infections in other parts of the body or asymptomatic patients should be tracked within the past 3 months.

(4) Treatment of gonorrhea with complications:

If uncomplicated anogenital gonococcal infection is not treated promptly or improperly, the infection may spread further and lead to local or systemic complications. The most common complication in men is epididymitis, and the most common complications in women are pelvic inflammatory disease (PID) and Bartholinitis. In addition to a sufficient course of treatment (10 days) for gonorrhea with complications, the treatment of mixed infections with multiple pathogens should also be considered, such as chlamydia or (and) anaerobic bacteria infections. The treatment plan should include antibiotics against these pathogens.