What is obstructive pulmonary disease? Be alert to these reasons

Nowadays, the incidence of obstructive pulmonary disease is increasing. The causes of this disease include infection, smoking, air pollution and allergies. For some people, the disease is caused by genetics.

Causes

1. Chronic bronchial inflammatory damage. Various factors that cause chronic bronchitis include infection, smoking, air pollution, occupational dust and long-term inhalation of harmful gases.

2. Disturbance of protease-antiprotease balance. It is currently believed that certain proteolytic enzymes in the body have damaging effects on lung tissue, while antiproteases have inhibitory effects on various proteases such as elastase. Maintaining a balance between proteases and antiproteases is an important factor in protecting the normal structure of lung tissue from damage.

3. Genetic factors. The occurrence of emphysema is also related to genetic factors. α1-AT in normal human serum is inherited as an autosomal recessive gene.

【symptom】

1. Coughing up phlegm: After coughing, people usually cough up a small amount of mucous phlegm, and some patients have more in the early morning.

2. Wheezing and chest tightness: These are not specific symptoms of COPD, but some patients, especially those with severe disease, experience wheezing.

3. Chronic cough: The cough is intermittent at first and is more severe in the morning. Later, the cough occurs in the morning and evening or throughout the day, but the cough is not obvious at night.

4. Systemic symptoms: Patients with more serious conditions may experience systemic symptoms, such as weight loss, loss of appetite, peripheral muscle atrophy and dysfunction, depression and/or anxiety, etc.