What are the effects and functions of processed Cyperus rotundus?

If you don’t know much about the effects and functions of processed Cyperus rotundus, you naturally don’t know how to use it correctly. In fact, some studies have found that it can relax the smooth muscles of the uterus, and can relieve fever, calm and relieve pain.

1. Suppressing the uterus

The fluid extract can inhibit the contraction of the isolated uterus of rabbits, cats, dogs, etc., and has a relaxant effect on the uterine smooth muscle, similar to that of angelica, but with weaker effect.

2. Estrogen-like effects

Subcutaneous injection and administration to ovariectomized rats can both cause epithelial keratinization. This suggests that Cyperus rotundus has a weak estrogen-like effect. The volatile oil cyperene has the strongest effect, followed by cyperone.

The sesquiterpenes in its volatile oil have the activity of inhibiting prostaglandin synthesis. These are all related to its ability to regulate menstruation and relieve pain.

(III) Relieving spasms and promoting bile secretion

The alcohol extract has a direct inhibitory effect on ileal smooth muscle and a protective effect on bronchospasm in guinea pigs induced by histamine spray.

The decoction of this product can promote the bile secretion of anesthetized dogs and still has a promoting effect on the bile secretion of rats after CCl4 liver injury.

(IV) Antipyretic, sedative, analgesic, anti-inflammatory

1. Antipyretic: The alcohol extract has an antipyretic effect on yeast-induced fever in rats. After 39 minutes, the normal body temperature of rats can be significantly reduced. It has a stronger cooling effect than chlorpromazine, but the duration of action is shorter.

2. Sedation: Intraperitoneal injection of subthreshold doses of sodium pentobarbital has a synergistic hypnotic effect in mice. After intravenous injection of volatile oil into rabbits, the righting reflex disappeared rapidly, as did the pain response and corneal reflex, and there was rigidity of the limbs.

3. Anti-inflammatory: Intraperitoneal injection of the alcohol extract into rats has a significant inhibitory effect on the foot swelling caused by carrageenan and formaldehyde. Its effect is stronger than that of hydrocortisone 5-10 mg/kg, and its active ingredients are triterpenoid compounds of Cyperus rotundus.

4. Analgesia: Subcutaneous injection of the alcohol extract into mice can significantly increase the pain threshold. The analgesic effect of 5 ml/kg oral administration of triterpenoid compounds of Cyperus rotundus is equivalent to that of 30 mg/kg acetylsalicylic acid.