What is a hyperplastic anemia bone marrow picture?

Many people have heard of hyperplastic anemia, which is a general term for many types of anemia. However, few people understand the bone marrow picture of hyperplastic anemia. Strictly speaking, bone marrow image is a manifestation of the bone marrow. Many clinical diagnoses are also made based on bone marrow image. So what is the bone marrow image of hyperplastic anemia?

1. Hyperplastic anemia: When the bone marrow shows a decrease in peripheral red blood cells or hemoglobin due to accelerated destruction of red blood cells or reduced production due to some reason, it is called anemia. Hyperplastic anemia is a comprehensive name for a group of diseases that cause anemia. It is classified according to cell morphology. The bone marrow manifestations have certain commonalities, but the diagnosis cannot be made solely based on the morphological description of bone marrow cells.

2. Bone marrow manifestations are: ① The proliferation is obviously active or active, the erythrocyte system is dominant, and the ratio of the granulocyte system to the erythrocyte system is lower than the normal value. ② The most common erythrocytes in the erythrocyte system are mesoblasts II and metablasts I. The number of mitotic figures of erythrocytes also increases. In addition, polyphilic erythrocytes and stippled erythrocytes can be seen in mature erythrocytes. Howell-Jolly bodies and Cabot rings can be seen in the cytoplasm of nucleated red blood cells or in the cell bodies of mature red blood cells. ③The granulocyte system is relatively reduced. ④There is no significant increase or decrease in the megakaryocyte system, and platelets are normal. When autoimmune hemolytic anemia is combined with thrombocytopenia (Evans syndrome), there may be an increase in megakaryocytes and a decrease in platelets.

3. Blood picture shows: ① The number of reticulocytes is increased or normal, with occasional nucleated red blood cells. Mature red blood cells may be slightly uneven in size and may include atypical red blood cells, polyphilic red blood cells, stippled red blood cells, and Howell-Jolly bodies and Cabot rings may be seen in the cell bodies of mature red blood cells or in the cytoplasm of nucleated red blood cells. ② The total white blood cell count is normal or slightly increased or decreased. When increased, the granulocyte count increases or the nuclear left shift occurs; when decreased, the lymphocyte count increases relatively. Generally, there are no immature granulocytes in the peripheral blood, but a small number of intermediate and late granulocytes can be seen when anemia is severe. ③The platelet count is normal or slightly low.