Glycyrrhizic acid has such a wide range of uses

Glycyrrhizic acid is a sweet substance that can be used in daily seasonings and added to sauces. Due to its sweet taste, glycyrrhizic acid can also be added to medicines to treat some physical diseases. It can also be used externally on the skin to protect against the sun and whiten the skin.

Glycyrrhizic acid use

1. Can be used as a sweetener, flavoring agent, and flavor enhancer.

2. It is commonly used in our country for sauces, sauce products, pickles, etc. Due to its various physiological activities, it has a significant effect on nourishing and growing hair, and can be used as an additive in hair nutrition products and skin care products. Using it in skin care products can enhance the efficacy of other active ingredients in sun protection, whitening, relieving itching, conditioning and scar healing.

Overview

Licorice, as a commonly used Chinese medicine, has been accepted and used by people. Its main ingredients are glycyrrhizin, glycyrrhizin, glycyrrhizin flavonoids, quercetin, formononetin, and quercetin. It has detoxification, anti-inflammatory, antitussive, anti-tumor, anti-ulcer and antibacterial effects. At the same time, glycyrrhizin has an inhibitory effect on the proliferation of HIV; glycyrrhizic acid has an inhibitory effect on myeloma and ascites liver cancer. Glycyrrhizic acid has obvious antidiuretic effect; liquiritigenin and isoliquiritigenin have anti-ulcer and antispasmodic effects; licorice flavonoids also have antioxidant and antibacterial effects.

There are three kinds of licorice medicinal materials recognized by the national pharmacopoeia, namely the dried roots and rhizomes of licorice, licorice inflated fruit and licorice glabra. Among them, licorice has the widest distribution, the highest yield and the best quality. Licorice is a traditional Chinese medicinal material with a long history of use and is well-known both at home and abroad. As early as the Warring States Period, there were records of using licorice to treat diseases, which is more than 2,500 years ago.

The "Shennong Bencao" of the Eastern Han Dynasty called licorice "beautiful grass" and "dense sweet" and listed it as a top-grade product. Traditional Chinese medicine believes that licorice is sweet and mild in taste. It is a good medicine for nourishing the spleen and replenishing qi, relieving cough and illness, relieving pain, harmonizing various medicines, and detoxifying. The US FDA lists licorice extract as a safe and non-toxic substance. Scientific research has shown that licorice mainly contains glycyrrhizic acid and the flavonoid glycyrrhizin (glycyrrhizin). Licorice extract is an additive with multiple functions such as antibacterial, anti-inflammatory, detoxification and deodorization.

Determination method

Method name: Licorice extract powder - Determination of glycyrrhizic acid - Capillary zone electrophoresis

Scope of application: This method uses capillary zone electrophoresis to determine the content of glycyrrhizic acid in licorice extract powder.

This method is applicable to the Chinese medicine preparation licorice extract powder.

Principle of the method: The glycyrrhizic acid in licorice extract powder was quantitatively analyzed by capillary zone electrophoresis with UV detection wavelength of 228nm and voltage of 14kV, using 50mmol/L borax solution as background electrolyte and hydrochlorothiazide as internal standard.