What are the precautions for taking oral thrombolytic drugs?

Because of arterial thrombosis, venous thrombosis, and soreness in many people's blood vessels or local skin, people will take some oral thrombolytic drugs. Oral thrombolytic drugs are relatively effective and can reach the lesions directly. They are of great help no matter which part of the body the soreness appears. However, it should be noted that during the period of taking the drugs, it is not suitable for patients with internal bleeding or those in special periods.

Basic information: Drug name: Thrombolytic drugs. Main indications: Deep vein thrombosis, peripheral arterial embolism, acute myocardial infarction, etc. Adverse reactions: Skin and mucosal bleeding, ecchymosis, visceral bleeding, etc. Main contraindications: Visceral bleeding, hemorrhage, history of stroke, intracranial tumors, etc.

Scope of application: It is used for thromboembolic diseases, such as deep vein thrombosis, peripheral arterial embolism, acute myocardial infarction, acute pulmonary embolism, acute ischemic stroke, etc. Common adverse reactions include superficial bleeding, such as bleeding and ecchymosis on the skin, mucous membranes and vascular puncture sites, as well as visceral bleeding, such as gastrointestinal bleeding, hemoptysis, hematuria, retroperitoneal bleeding, cerebral hemorrhage, etc. Severe bleeding may lead to death. Occasionally, hemolytic anemia, jaundice and elevated ALT may occur; secondary embolism after thrombolysis (pulmonary embolism, cerebral embolism, etc.) and allergic reactions.

Precautions: The use of thrombolytic drugs requires prevention of severe bleeding. It is contraindicated for patients with active visceral bleeding, previous hemorrhagic stroke, ischemic stroke or cerebrovascular event within 1 year, intracranial tumors, suspected aortic dissection, etc. It is contraindicated in patients with severe liver or renal impairment. It should be used with caution in pregnant and lactating women, women who have given birth within 10 days, patients who have undergone tissue biopsy, venipuncture, major surgery, patients with severe gastrointestinal bleeding, and those with bleeding tendency or coagulation disorder secondary to liver and kidney disease. The combined use of thrombolytic drugs with warfarin, antiplatelet drugs, heparin and other drugs that affect coagulation may increase the risk of bleeding. Use a certain thrombolytic drug for thrombolytic treatment. After the blood vessels are reopened, if infarction occurs again, other thrombolytic drugs can be used.

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