The phenomenon of embryonic arrest is not uncommon nowadays, which is a big blow and harm to many pregnant mothers. Therefore, we must understand what the precursors of embryonic arrest are. For example, the most common symptoms are the disappearance of early pregnancy reactions such as nausea and vomiting, or vaginal bleeding. Of course, if you want to confirm the diagnosis, you still have to go to the hospital for a comprehensive examination. 1. Symptoms If embryo arrest occurs, all pregnancy reactions of the pregnant mother will gradually disappear. First of all, there will be no more early pregnancy reactions such as nausea and vomiting, and the feeling of breast swelling will also be reduced. Then there will be vaginal bleeding, often dark red bloody leucorrhea. Finally, there may be lower abdominal pain and expulsion of the embryo. The above symptoms vary from person to person. Some people may not even show any signs, but may directly experience abdominal pain and then miscarriage, or the embryo may stop developing without any symptoms and be discovered through routine B-ultrasound examination. 2. Causes of embryonic arrest refers to the cessation of embryo development due to some reasons in early pregnancy. Ultrasound examination may show an irregular fetal bud or fetal shape in the gestational sac, no fetal heartbeat, or a withered gestational sac. Clinically, it falls into the category of miscarriage or stillbirth. There are many reasons for embryonic arrest. 3. Sperm problems Environmental pollution, food safety, radiation and other factors are damaging men’s sperm, causing a sharp increase in the number of men suffering miscarriages[2]. The promotion of emerging technologies such as sperm DNA fragmentation detection is very slow. The chromosomes in the sperm nucleus carry the genetic code of each human individual. When the human sperm and egg combine to form a fertilized egg, the sperm will pass the genetic information in the nucleus to the offspring to ensure embryonic development. Therefore, sperm chromosome abnormality or sperm nuclear immaturity can lead to abnormal or terminated embryonic development and is the most common male factor causing female miscarriage. Sperm DNA fragmentation detection[3] is one of the latest methods to evaluate the functional status of sperm nucleus. Therefore, it is generally recommended to first rule out the male cause after the fetus stops moving, and check the male's sperm deformity rate and sperm DNA fragmentation rate (DFI for short, which is sperm DNA fragmentation test). 4. Endocrine disorders Embryo implantation and continued development depend on the coordination of a complex endocrine system. Abnormalities in any link can lead to miscarriage. During the early development of the embryo, three important hormone levels are required: estrogen, progesterone, and human chorionic gonadotropin. As for the mother, if her own endogenous hormones are insufficient, it cannot meet the needs of the embryo and may cause embryo arrest and miscarriage. |
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