The efficacy of Atractylodes macrocephala and Chicken's gizzard lining

Traditional Chinese Medicine is a relatively important discipline in today's clinical medicine. This is mainly because TCM treatments have relatively few side effects and have the effect of warming and nourishing the body. In traditional Chinese medicine, the most commonly used medicinal material is Chinese herbal medicine. There are many kinds of traditional Chinese medicine, and Atractylodes macrocephala and Chicken Gizzard Stone are two common and important medicinal materials. So, what are the effects of using Atractylodes macrocephala and Chicken Gizzard Stone together?

1. Diuretic effect

It has a significant and lasting diuretic effect and is effective on various animals such as rats, rabbits, and dogs. When 0.05-0.25 g/kg of the decoction was injected intravenously into unanesthetized dogs, the urine volume increased by more than 9 times, and was still higher than normal 5 hours after administration; when 1-3 g/kg was administered by gavage, the urine volume increased by 2-6 times compared with before administration, and in most cases it was still higher than normal 6-7 hours after administration. The decoction and fluid extract of Atractylodes macrocephala were injected intravenously at 1.0 g/kg into rats, and by gavage or intraperitoneal injection at 1.0 g/kg into rabbits, all of which produced obvious and lasting diuretic effects. Atractylodes not only increases the excretion of water, but also promotes the excretion of electrolytes, especially sodium, and the excretion of sodium is better than the excretion of water. It also does not affect the antidiuretic effect of the posterior pituitary hormone. Therefore, Atractylodes macrocephala increases water excretion not mainly by affecting the active reabsorption of water, but rather is secondary to the reduction in electrolyte reabsorption. It has a mercury-salt-like effect in excreting chlorine and sodium; it also has the acetazolamide-like characteristics of increasing the carbon dioxide capacity and pH value in urine, increasing potassium excretion, and reducing ammonium excretion. There are a few trials on its diuretic effect in humans, but no conclusive confirmation is available.

2. Hypoglycemic effect

When rabbits were given the decoction or extract by gavage, their blood sugar level was slightly lowered. Intragastric administration of the decoction to rats accelerated the assimilation of glucose in the body and thus lowered blood sugar. Oral administration of the decoction to mice has the effect of protecting the liver and preventing the reduction of glycogen caused by carbon tetrachloride.

3. Strengthening effect

Oral administration of 1 mol or 6 g/kg of Atractylodes macrocephala decoction can promote weight gain and enhance swimming endurance in mice. Atractylodes macrocephala can enhance the phagocytic function of the reticuloendothelial system, activate the reticuloendothelial system of mice, promote the phagocytic function of peritoneal macrophages in mice, and significantly increase the phagocytic percentage of macrophages, phagocytic index and lysosomal digestion on average compared with the control group. In cases of leukopenia, Atractylodes macrocephala has the effect of increasing white blood cells. Atractylodes can also increase the lymphocyte transformation rate and natural rosette formation rate, promote cellular immune function, and significantly increase IgG. It shows that Atractylodes macrocephala has the effects of strengthening the spleen and stomach, strengthening the body and improving disease resistance.