How to treat urine protein 2+?

Urine protein refers to the presence of protein in the urine excreted by the human body, also known as urine protein. Normal people’s urine actually contains a small amount of small molecule urinary protein, but because the content is so small, it is almost impossible to detect it, and the test result is negative (-). When the protein content in the urine rises to a certain amount, the test result is positive (+). Urine protein 2+ (++, two plus signs) is the result of a 24-hour urine protein quantitative test. This means that 1L of urine contains 1.0 to 2.0g of protein, or 1.0 to 2.0g/24H. Its excessive presence affects the human kidney function, so how should it be treated?

Urinary protein causes worse tubular interstitial hypoxia: Proteinuria requires additional energy to reabsorb and digest large amounts of protein, which can cause tubular cell hypoxia and thus tubular cell damage. There is increasing evidence that proteins can directly regulate tubular cell function, alter their growth characteristics and their phenotypic expression of cytokines and matrix proteins, leading to the release of PDGF, FN, and MCP-1 from the basal side of the tubules, inducing a fibrotic process.

Although proteinuria is not particularly obvious, if you have chronic kidney disease, you must check whether this symptom occurs and take timely treatment measures. Proteinuria in chronic kidney disease is not only a sign of kidney damage, but also a large amount of protein excreted through the renal tubules can trigger inflammation and fibrosis of renal tubular epithelial cells, thereby accelerating the development of chronic kidney disease.

Large amounts of proteinuria are one of the main risk factors for the progression of chronic kidney disease to end-stage renal failure, and therefore should be an important goal in the treatment of chronic kidney disease. Mesangial toxicity of urinary protein: In the proteinuria nephropathy model, apolipoprotein B and apolipoprotein A of low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL) are deposited in the glomeruli. These aggregations can eventually lead to glomerular sclerosis. Toxic effect of urinary protein on proximal tubular cells: When proteinuria occurs, the amount of protein entering the renal tubular epithelial cells increases, which increases the activity of lysosomes, indicating that protein causes lysosomes to overflow into the tubular cytoplasm. The subsequent cell damage can stimulate inflammation and scar formation.

Active anti-infection treatment should be carried out to eliminate factors that aggravate the disease. Strict control of diet, a low-salt, low-fat, high-quality, low-protein, and low-calorie diet can effectively alleviate the condition. Suggestions: Strict dietary control, a low-salt, low-fat, high-quality, low-protein, and low-calorie diet can effectively alleviate the condition. Adjust your mood in life, avoid fatigue, and prevent colds, infections and other triggering and aggravating factors.