Is it better to transfer fresh embryos or frozen embryos?

The IVF method can effectively increase the chances of pregnancy for women and ensure the health of the fetus. However, any woman who undergoes IVF will go through the process of embryo transfer. Embryo transfer is divided into fresh embryo transfer and frozen embryo transfer. These two methods have caused controversy among many people. So is it better to transfer fresh embryos or frozen embryos? Is it better to transfer fresh embryos or frozen embryos?

First, is it better to transplant fresh embryos or frozen embryos? Is it better to transplant fresh embryos or frozen embryos? We know that after successful in vitro fertilization, a major factor affecting the success rate of in vitro fertilization is embryo transplantation. The so-called fresh embryo transfer is the direct embryo transfer in a relatively fresh cycle without freezing and thawing. The process includes egg retrieval, in vitro fertilization, embryo culture, and direct embryo transplantation into the uterine cavity. Frozen embryo transfer is the process of freezing the embryos using embryo freezing technology after embryo culture. The embryos are then thawed and revived at a specific time point in a menstrual cycle after the egg retrieval cycle, and then transplanted into the uterine cavity.

Second, some people believe that after the embryo is cultured in vitro to the appropriate stage, it does not go through additional steps that may affect the embryo, such as interference from embryo freezing and thawing. Fresh embryo transplantation can preserve the embryo's developmental potential to the greatest extent. The embryo's condition at this time should be the best and most reliable, and its development success rate is also relatively high.

Third, during the frozen-thaw embryo transfer cycle, the freezing and thawing process of the embryo may cause damage to the embryo's ultrastructure or biological macromolecules (DNA, RNA, protein, etc.), which may reduce the embryo's developmental potential.

Is it better to transplant fresh embryos or frozen embryos? Is it better to transplant fresh embryos or frozen embryos? In fact, if fresh embryo transplantation is chosen, when using ovulation-inducing drugs to obtain eggs, there is a certain possibility that the actual development speed of the endometrium will be artificially changed. Therefore, in such a cycle, the actual development speed of the endometrium and the embryo may not be consistent. So in general, based on the current research, there is no difference between frozen embryos and fresh embryos, so expectant fathers and mothers who want to have in vitro fertilization do not have to worry too much.