What are the reasons for high tsh values?

TSH stands for thyroid stimulating hormone, which plays a very important role. If it is found to be too high during the examination, it is very likely that you have a thyroid disease. Studies have found that there are many reasons for high TSH values, among which primary hypothyroidism, exogenous thyroid-stimulating hormone-secreting tumors (lung, breast) and other diseases are the most common. In addition, it may also be in the recovery period of subacute thyroiditis.

1. What does tsh value mean?

TSH (thyrotropin, thyroid stimulating hormone, TSH) is the Chinese name for thyroid stimulating hormone. TSH is a hormone secreted by the pituitary gland that promotes the growth and function of the thyroid gland. Human TSH is a glycoprotein containing 211 amino acids, with carbohydrates accounting for approximately 15% of the entire molecule. The entire molecule consists of two peptide chains - the α chain and the β chain. TSH comprehensively promotes the function of the thyroid gland. The earlier effect is to promote the release of thyroid hormones, and the later effect is to promote the synthesis of T4 and T3, including strengthening the activity of the iodine pump, enhancing the activity of peroxidase, promoting the synthesis of thyroglobulin and tyrosine iodination, etc. TSH promotes the metabolism of thyroid epithelial cells and the synthesis of intracellular nucleic acids and proteins, causing the cells to proliferate in a tall columnar shape, thereby enlarging the gland.

2. What are the reasons for high TSH?

TSH, also known as "thyroid hormone", can promote the metabolism of thyroid epithelial cells and the synthesis of intracellular nucleic acids and proteins, causing the cells to proliferate in a tall columnar shape, thereby enlarging the gland. The pituitary gland secretes TSH, which is on the one hand influenced by the thyrotropin-releasing hormone (TRH) secreted by the hypothalamus, and on the other hand influenced by the feedback inhibitory effects of T3 and T4. The two antagonize each other and form the hypothalamus-pituitary-thyroid axis.

Normal value of thyroid stimulating hormone : Adults: 2~10mU/L. >60 years old: Male: 2.0～7.3mU/L. Women: 2.0~16.8mU/L. Children: (4.5±3.6)mU/L. Increased TSH: primary hypothyroidism, Hashimoto's disease with hypothyroidism, exogenous thyroid-stimulating hormone-secreting tumors (lung, breast), and recovery period of subacute thyroiditis. Intake of metallic lithium, potassium iodide, and thyrotropin-releasing hormone can increase thyroid-stimulating hormone.

Patients with hyperthyroidism secrete too much thyroid hormone, which promotes the absorption of intestinal sugar, accelerates sugar oxidation and glycogenolysis, and also promotes fat decomposition and oxidation, which can significantly increase the body's heat production and heat dissipation, accelerate protein metabolism, and cause a negative nitrogen balance (consumption is greater than intake). People often have symptoms such as fatigue, weakness, and muscle atrophy. The consumption of these energies makes hyperthyroidism patients eat more and lose weight faster. Therefore, patients with hyperthyroidism must ensure adequate daily intake of calories and nutrients to meet the needs of the human body.

Therefore, when TSH is high, you should not only go to the hospital to seek medical treatment in time, but also pay attention to maintaining your own health. Even if you have advanced medical skills and treatment, it is useless if you don’t cooperate and keep your body healthy! I hope everyone can pay attention to their own health!