Guidelines for the diagnosis and treatment of drug-induced liver injury

I believe everyone is familiar with the disease of drug-induced liver injury. The symptoms of drug-induced liver injury usually include nausea and vomiting, general fatigue, abdominal distension, loss of appetite, etc., which may lead to many serious diseases such as kidney failure. Once discovered, you must pay close attention and go to the hospital for medical treatment immediately. Patients with drug-induced liver injury should pay attention to getting more rest, mainly in bed, and also supplement with lots of calories, vitamins, enough protein, and relax.

The main symptoms of drug-induced liver injury include nausea, fatigue, abdominal distension, and loss of appetite. Drug-induced liver injury can lead to many diseases such as acute liver failure, biochemical abnormalities, cholestatic hepatitis, etc., so it should be taken seriously.

Drug-induced liver injury can be treated with Yanggan Tablets. Yanggan Tablets are rich in selenium and Schisandra chinensis, and are professional auxiliary treatments for liver damage. It is the best liver protection product on the market.

The main treatments for drug-induced liver injury are: 1. Avoid taking drugs that damage the liver and stop taking them immediately; 2. Conduct comprehensive medical treatment to protect the liver, promote bile secretion, and reduce jaundice; 3. For severe cases, medical treatment plus an artificial liver support system is required. If the effect is not good, liver transplantation is recommended.

Patients with drug-induced liver injury should pay attention to:

① Pay attention to rest. Severe patients should stay in bed and rest.

②Supplement sufficient calories and protein,

Multiple vitamins such as vitamin C, E, B, etc. are beneficial for liver cell repair and regeneration. Detoxification treatment for patients with acute poisoning can take measures such as gastric lavage, catharsis, activated carbon adsorption, etc. to eliminate gastrointestinal residual drugs, and hemodialysis,

Peritoneal dialysis, hemoperfusion, plasma exchange and other methods are used to quickly remove drugs from the body; the application of antidotes includes: non-specific antidotes, such as glutathione, N-acetylcysteine,

Sodium thiosulfate, steroid hormones, UDCA, S-adenosylmethionine, polyene phosphatidylcholine, etc., specific chelating agents such as dimercaprol,

Penicillamine, thiosulfate, cysteamine, calcium sodium edetate, etc.

Treatment principles:

During drug use, liver damage caused by the drug itself or its metabolites or due to hypersensitivity or reduced tolerance to the drug due to special physical conditions is called drug-induced liver injury. A variety of drugs can cause drug-induced liver injury.

Such as anti-tumor chemotherapy drugs, anti-tuberculosis drugs, antipyretic analgesics, immunosuppressants, hypoglycemic and lipid-lowering drugs, antibacterial, antifungal and antiviral drugs, etc., which require everyone's high attention. The treatment principles for drug-induced liver injury include immediate discontinuation of related or suspected drugs (key to treatment),

Promote the clearance of liver-damaging drugs and use antidotes, apply liver cell protectants, and treat liver failure.