fibromatosis

Fibrous tissue tumor-like hyperplasia is a less common proliferative disease, which is commonly known as fibroma. Patients with fibromatosis are generally children, and the probability of disease in the limbs is higher. Moreover, patients generally experience swelling and bulging of the skin. Currently, the most common medical treatment is surgery, and the probability of recurrence after surgery is not high. So, what should we do about fibromatosis?

1. What is fibromatosis?

The fibrous connective tissue proliferates in a tumor-like manner, forming tumor-like masses, also known as fibromatosis. It includes many types, about more than ten kinds. Common ones include nodular fasciitis, proliferative fasciitis, proliferative myositis and zona fasciitis. The difference between tumor-like fibrous tissue hyperplasia and fibroma is that it grows locally infiltratively and has no capsule. In addition to fibroblasts, a large number of myofibroblasts are also seen. Sometimes the fibroblasts proliferate more actively, with abundant cells, hypertrophic nuclei, and even mild atypia and a few normal nuclear division images. If the resection is incomplete, the disease may recur multiple times but will not metastasize. This type of lesion can be seen in infants, children and adults, depending on the type, but is generally more common in children. It can occur in any part of the soft tissue, but it is more common in the subcutaneous tissue, fascia, and muscles of the limbs and abdominal wall.

2. What to do if subcutaneous fibrous tissue tumor-like hyperplasia

Fibrous tumor-like hyperplasia is a benign lesion. The specific cause of the disease is not very clear. It may be related to chronic inflammatory stimulation. This disease is not the same as lipoma and there is a possibility of recurrence after resection. For locks that have been removed more thoroughly, the chance of recurrence will be relatively low. Please pay attention to observe yourself after the operation.

3. Prevention of recurrence of abdominal wall fibrous tissue tumor-like hyperplasia

Fibrous tumor-like hyperplasia of the abdominal wall does not metastasize but is prone to recurrence. It is reported that the recurrence rate can be as high as 50% to 66.8%, and mainly occurs in the age group of 18 to 30 years old.

Plukker et al. believed that tumor recurrence is related to the range of surgical resection and tumor size. The larger the tumor, the more likely it is to recur. Tumors larger than 10 cm have the highest postoperative recurrence rate. A few abdominal wall fibrous tumor-like hyperplasias may exist for a long time without growing if surgical resection is not complete.

However, some scholars have reported that repeated recurrence and multiple surgeries may lead to tumor metastasis. Fibrous tumor-like hyperplasia of the abdominal wall may regress spontaneously, and even some giant abdominal wall fibrous tumor-like hyperplasia may shrink or disappear naturally without any treatment.