In fact, everyone has moles, and moles are usually black. Under normal circumstances, if the mole is not particularly obvious, it will not have any impact on a person's health and life. Sometimes it is even one of a person's characteristics. Therefore, many people in life do not care too much about black "moles". In fact, black moles are sometimes distinguished from melanoma tumors. If it is a melanoma tumor, then the harm to the human body can be great. So what is the difference between a mole and a melanoma? What impact will a melanoma have on human health? For those who have already developed a melanoma, how can they completely cure this problem? All malignant melanomas are made up of only one type of malignant cell, the malignant pigment-producing cells called melanocytes, but they have some minor differences in their morphology, such as spindle-shaped or cylindrical. Although the morphology of ocular melanoma is a meaningful indicator of its behavior, in cutaneous melanoma, the morphology of each type is essentially similar. All melanocytes contain small granules of pigment, even when their cells are not black or dark brown. In all cases, the enzyme necessary to produce melanin, the black pigment, is present. When malignant melanomas spread, they usually do not produce melanin and are therefore called apigmented, but apigmented and pigmented melanomas are almost equally aggressive. Malignant melanoma most commonly develops on the skin, but 10% develop in the eye. The most common types of melanoma in the skin are called superficial spreading melanoma and micronodular melanoma, terms that refer to the exaggerated patterns of disease they describe. Malignant melanoma can develop in unusual locations, such as under the nails of your fingers or toes or on the lining of your mouth, vagina, or anus. Primary malignant melanomas are also found in the pigmented tissue covering the brain (meninges). It is important not to confuse malignant melanoma under the nail with a fungal infection, although this mistake is sometimes made in the early stages of the disease. Malignant melanoma of the eye develops in the colored area at the front (iris), in the structure behind the iris that controls the shape of the lens (ciliary body), and in the pigmented layer that covers the retina at the back of the eye. Melanocytes Most malignant melanomas originate from melanocytes of normal skin, and about 40% to 50% occur in pigmented nevi (see Section 125 Nevi and Dysplastic Nevi). Malignant melanoma is rare in children but can arise from very large moles that are present at birth. Halo nevi usually disappear on their own but in rare cases they may become melanoma. Although melanoma is more likely to occur during pregnancy, pregnancy does not increase the likelihood of a mole turning into melanoma. Moles often change in shape and size during pregnancy. The following danger signs indicate that a pigmented nevus may become malignant: changes in size, color, redness, whiteness, or blueness, especially the spread of the pigmented area to the surrounding normal skin; changes in surface features, texture and shape; especially inflammatory reactions in the skin around the nevus, which may manifest as bleeding, ulcers, itching, or pain. Malignant melanomas vary in size, shape, and color (usually pigmentation) and in their tendency to invade locally and to metastasize to distant sites. The tumor spreads rapidly and can cause death within months of diagnosis. Early, very superficial lesions can have a 100% cure rate within 5 years. Therefore, the cure rate depends on early diagnosis and early treatment. Finally, I would like to remind you that if you suddenly grow a so-called black "mole", you must receive targeted treatment, so as to best avoid the harm of melanoma to your body. At the same time, if it is found to be a melanoma, you must receive targeted treatment, so as to stay away from the trouble of tumors. |
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