How to treat gout arthritis? Three methods are most effective

Arthritis is a common clinical disease. In clinical practice, gouty arthritis is a common type of disease. So, how to treat gouty arthritis? The following article will give you three tips.

1. Treatment of acute phase

The triggering factors should be eliminated and acute attacks of arthritis should be controlled. Commonly used drugs include:

(1) Nonsteroidal anti-inflammatory drugs are the preferred analgesics in the acute phase, such as diclofenac sodium or diclofenac potassium, or celecoxib, meloxicam, etc. Stop medication after symptoms are controlled. Pay attention to monitor serum creatinine levels during application.

(2) Colchicine can be considered when nonsteroidal anti-inflammatory drugs are ineffective. Initially, take a small amount orally until the symptoms are relieved or the drug side effects occur and then stop. Monitor for adverse reactions during medication.

(3) Glucocorticoids: For patients with renal insufficiency, glucocorticoids can be considered in the acute phase, and intramuscular injection of Depoxetine is often used clinically.

2. Treatment during remission

The main purpose is to lower blood uric acid levels and prevent another acute attack.

(1) Allopurinol, a drug that inhibits uric acid production, should be started from a small dose and gradually increased according to the uric acid level.

(2) Benzbromarone, a drug that promotes uric acid excretion.

It should be emphasized that uric acid-lowering drugs may induce acute arthritis and should not be used in the acute phase, and such drugs should be started at low doses.

3. Treatment of asymptomatic hyperuricemia

General treatment includes weight loss, blood lipid control, reduction of unnecessary diuretic use, diet control, etc. At the same time, active treatment is given to co-occurring diseases such as hypertension, hyperlipidemia, and hyperglycemia. There is currently no consensus on the timing of the use of uric acid-lowering drugs. Since about 5% to 15% of patients with asymptomatic hyperuricemia develop gout, if they have cardiovascular disease or other high-risk factors, they should start regular uric acid-lowering treatment when the blood uric acid level remains above 480umol/L. If there are no high-risk factors such as cardiovascular disease, continuous uric acid-lowering treatment can be started when the blood uric acid level is higher than 540umol/L.