What causes depression?

Nowadays, many people suffer from depression for a long time. Depression can make a person lose confidence and even stay in the room for a long time and dare not go out. These are all harmful to us, so everyone should understand depression clearly and choose appropriate methods for treatment. There are many general causes of depression, and the key lies in the treatment method.

Causes

To date, the cause of depression is still unclear, but it is certain that many biological, psychological and social environmental factors are involved in the pathogenesis of depression. Biological factors mainly involve genetics, neurochemistry, neuroendocrine, neural regeneration and other aspects; the psychological susceptibility factors closely related to depression are pre-morbid personality traits, such as depressive temperament. Encountering stressful life events in adulthood is an important trigger for the onset of clinically significant depressive episodes. However, these factors do not act alone. Currently, it is emphasized that the interaction between genetics and environmental or stress factors, as well as the timing of this interaction, has an important impact on the occurrence of depression.

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Treatment strategy

The treatment of depressive episodes should achieve three goals: 1. Improve the clinical cure rate and minimize the disability and suicide rates. The key is to completely eliminate clinical symptoms; 2. Improve the quality of life and restore social functions; 3. Prevent relapse.

Drug treatment

Medication is the main treatment for moderate or severe depressive episodes. Commonly used drugs mainly include selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, norepinephrine and specific serotonergic antidepressants, etc.

Other treatments

For patients with depressive episodes with obvious psychosocial factors, psychotherapy is often required in combination with drug treatment.