What are the side effects of Budd-Chiari syndrome?

People's bodies are easily troubled by a variety of diseases, and the occurrence of many diseases will have a great impact on the human body. Budd-Chiari syndrome is a common disease, most of which occur in the Western region. Because of the coagulation of the blood, the hepatic artery is formed, which will cause blockage of the vena cava and prevent blood from circulating normally. Although this disease is rare, it will occur in many newborns and may even gradually appear during embryonic development. The harm can be said to be quite large and may also affect life. Therefore, when this disease occurs, it is necessary to receive treatment as soon as possible to avoid continued worsening of the condition.

Hypercoagulable state and congenital developmental abnormalities are the most common causes of Budd-Chiari syndrome.

In Western countries, most cases of Budd-Chiari syndrome are due to a hypercoagulable state, leading to hepatic vein thrombosis. The inferior vena cava is often not involved, or it may be compressed by an enlarged liver, leading to stenosis or occlusion of the inferior vena cava. In Eastern countries, including China, the main problem is malformation of the inferior vena cava.

Congenital malformation of the inferior vena cava is formed during embryonic development and can be briefly introduced as follows.

During embryonic development, the inferior cardiac vein grows downward and the common hepatic vein grows upward, and then the inferior cardiac vein and the common hepatic vein connect to become the inferior vena cava. If for some reason the development of the two stops at a certain stage, it will lead to non-connection or incomplete connection of the inferior vena cava. Most dysplasias are membranous, webbed, cribriform, or membranous. This is the result of the inferior cardiac vein and the common hepatic vein just coming into contact during embryonic development and not yet fully connected.

Of course, hypercoagulable state of blood is also one of the reasons.

Some patients are caused by thrombosis in the hepatic vein, which can also extend to the inferior vena cava, causing obstruction of the hepatic vein and inferior vena cava. Other causes of Budd-Chiari syndrome can also occur, but they are less common.

Regardless of the cause of Budd-Chiari syndrome, two sets of symptoms may occur. One of them is varicose veins in the lower limbs.

The second is symptoms caused by hepatic vein obstruction, which are the same as those of portal hypertension.

In addition, there are superficial varicose veins in the chest wall, abdominal wall, and lower back. This is because the inferior vena cava is blocked, and venous blood cannot flow back from the inferior vena cava to the right atrium, causing the subcutaneous superficial veins of the chest, abdominal wall, and lower back to dilate and varicose, partially compensating for the return of the inferior vena cava, causing the venous blood in the lower limbs to bypass the dilated and varicose chest wall, abdominal wall, and lower back subcutaneous superficial veins to the superior vena cava, and then flow back to the right atrium.