From nephritis to uremia, see the stages of kidney disease

For patients with kidney disease, the harm is relatively large. It often starts with nephritis. If you do not pay attention to conditioning and good treatment, the disease may develop and gradually worsen. The worsening process of kidney disease can be divided into several stages, such as the inflammatory response stage, the renal function compensation stage, the renal function decompensation stage, etc. Through these stages, we can see the patient's lesions from severe nephritis to uremia.

CKD stage 1: inflammatory response stage

During this period, there is no obvious change in blood creatinine and renal function has not been damaged, which is usually called nephritis. This period is the easiest to cure, and the clinical indications are mostly proteinuria, occult blood, edema, and hypertension.

CKD stage 2: renal function compensation stage

During this period, the blood creatinine value was between 133-177μmoI/L. At this time, half of the kidney's nephrons can still function normally and can rely on their own compensatory functions to meet the body's daily needs. If regular treatment is received in time, clinical cure can be achieved.

CKD stage 3: renal decompensation

During this period, blood creatinine values ​​were between 178-442 μmoI/L. More than two-thirds or even more of the kidneys have been damaged, and the kidney's own compensatory function can no longer meet the body's daily needs.

Most patients have begun to feel fatigue, but the symptoms are still not obvious. If timely and regular treatment is received, there is still a 50% chance of achieving clinical cure.

CKD stage 4: renal failure

When blood creatinine exceeds 443μmoI/L, it has entered the stage of renal failure. At this time, renal function has declined to an irreversible stage and renal cells are being killed every moment.

At this time, many symptoms begin to appear, such as anemia, dizziness, fatigue, nausea, etc. The focus of treatment has become to prevent further necrosis of kidney cells and protect the remaining kidney function. Some hospitals have also begun to recommend hemodialysis to patients.

CKD stage 5: uremic stage

During this period, the blood creatinine value usually exceeds 707μmoI/L. 90% of the renal units of the patients have become necrotic, the volume of the kidneys has mostly shrunk to less than 6cm, and they have basically lost the ability to produce urine.

Most patients will experience very strong symptoms, such as dizziness, fatigue, nausea, vomiting, heart failure, anemia, etc., and these symptoms occur frequently. The significance of treatment at this time has become to maintain the patient's normal life as much as possible and reduce the patient's pain.