Can adrenal hyperplasia heal on its own?

In life, we all know that the adrenal glands are where urine is produced. If there is a problem with the adrenal glands, it means that there is a problem with our physical health. Most people have questions in their minds: can adrenal hyperplasia heal itself? In fact, adrenal hyperplasia cannot heal itself. Currently, adrenal hyperplasia is mainly treated through surgical treatment. Therefore, if you unfortunately suffer from adrenal hyperplasia, you should go to the hospital for treatment in time.

Adrenal hyperplasia and adrenal cortical hyperplasia are the activities and functional activities of medullary cells. These two diseases can increase the synthesis and release of catecholamines, causing hypercatecholamine syndrome, and the clinical manifestations of the two are similar.

Adrenal medullary hyperplasia is a disease that has only been taken seriously since the early 1960s. There is no clear conclusion on its cause. It has been found that it often coexists with other endocrine gland diseases, such as medullary thyroid carcinoma and hyperparathyroidism, and is one of the lesions of multiple endocrine neoplasia type II.

Adrenal hyperplasia treatment

The treatment of adrenal medullary hyperplasia is still mainly surgical. The majority of the hyperplastic bilateral adrenal glands are removed, leaving only part of the cortex to avoid adrenal cortical insufficiency after surgery.

Clinical manifestations of adrenal hyperplasia

Congenital adrenal hyperplasia, also known as adrenogenital syndrome or adrenal. Due to defects in important enzymes in the synthesis of adrenal cortex hormones, the synthesis of corticosteroids is abnormal.

In most cases, the adrenal glands secrete insufficient glucose-regulating hormones and salt-regulating hormones but excessive androgens, resulting in varying degrees of adrenal cortical insufficiency clinically, accompanied by masculinization in girls and precocious reproductive system in boys. In addition, there may be various syndromes such as hyponatremia or hypertension.

The adrenal medulla is almost entirely composed of chromaffin cells, which are brown in color and weigh about 1g. They mainly secrete adrenaline and norepinephrine. Their main function is to regulate the metabolism of sugar and fat and enhance cardiovascular contraction. The characteristics of adrenal diseases are similar to the imbalance of kidney yang and kidney yin in traditional Chinese medicine. Therefore, traditional Chinese medicine mainly focuses on regulating yin and yang when treating such diseases. The following are symptoms of adrenal gland disease.

Symptoms of adrenal gland disease

1. Weakness

It is the main symptom in the early stage, and the degree of fatigue is directly proportional to the severity of the disease. In severe cases, the patient may be unable to turn over or reach out to pick up objects. Severe muscle cramps may also be seen, especially in the legs. These muscle lesions may be related to disturbances in sodium and potassium homeostasis at the neuromuscular endplates.

2. Weight loss

The lack of cortisol caused by gastrointestinal disorders such as anorexia, nausea, vomiting, bloating, diarrhea, and loss of fat and muscle wasting factors such as storage can lead to weight loss, greatly reducing the possibility of adrenal crisis.

3. Pigmentation

Due to the lack of cortisol, the feedback inhibition on pituitary ACTH, melanocyte stimulating hormone (MSH) and lipotropin (LPH) is weakened, resulting in increased secretion of these hormones. ACTH and LPH contain α and β-MSH structures respectively, so pigmentation occurs on the skin and mucous membranes, and is particularly obvious in places of friction, palm lines, areola, scars, etc. Pigmentation is one of the main bases for distinguishing primary from secondary adrenal insufficiency. A sudden darkening of pigmentation may indicate a worsening of the disease.

4. Cardiovascular symptoms

Due to the weakened pressor response to catecholamines, blood pressure decreases, with orthostatic hypotension being the most common. X-ray showed a smaller heart shadow, electrocardiogram showed low voltage, and prolonged PR and QT intervals. Patients often experience dizziness, blurred vision, and orthostatic syncope.

5. Hypoglycemia

Patients have increased sensitivity to endogenous and exogenous insulin and are prone to hypoglycemia in conditions of hunger, gastrointestinal dysfunction, infection, etc.

6. Neurological symptoms

Such as apathy, drowsiness and even mental disorders.