Elevated aspartate aminotransferase

Do you know what causes elevated aspartate aminotransferase? Aspartate aminotransferase is a very important indicator in liver function tests. It can measure whether our liver is normal. If aspartate aminotransferase is elevated, it means that our liver has been damaged and liver function will be abnormal. Regarding the situation of elevated aspartate aminotransferase, let's take a look at the following introduction.

Do you know what aspartate aminotransferase is? Few people probably know about it, unless you have liver problems. If you have liver problems and go to the hospital for a check-up, there will be an aspartate aminotransferase test, which can well judge the abnormalities of our liver, especially the increase of aspartate aminotransferase.

1. Elevated levels of aspartate aminotransferase are also found in healthy people

In healthy people, transient elevation of aspartate aminotransferase may occur in situations such as acute soft tissue injury, strenuous exercise, and pregnancy.

2. Heart disease

Since the content of aspartate aminotransferase is highest in myocardial cells, acute myocardial infarction, myocarditis, and heart failure will cause an increase in alanine aminotransferase and aspartate aminotransferase, which is also one of the reasons for the increase in aspartate aminotransferase.

3. Liver cell damage

1. Liver cell damage caused by viral hepatitis is the most common cause of elevated aspartate aminotransferase. All types of acute and chronic viral hepatitis can significantly increase aspartate aminotransferase.

2. Liver cell damage caused by toxic hepatitis, alcoholic liver disease, cirrhosis and liver cancer, biliary tract disease, etc. can also lead to elevated aspartate aminotransferase.

3. Damage to liver cells caused by certain infectious diseases is also one of the reasons for elevated aspartate aminotransferase, such as pneumonia, typhoid fever, tuberculosis, infectious mononucleosis, etc.

How to treat high aspartate aminotransferase?

1. To treat elevated aspartate aminotransferase, choose appropriate liver-protecting and enzyme-lowering drugs. The most effective drugs for treating elevated aspartate aminotransferase levels caused by various causes are also different. When treating patients, they must choose medications according to the instructions of the attending physician, and avoid taking enzyme-lowering drugs blindly on their own to avoid aggravating the disease due to improper use.

2. To treat elevated aspartate aminotransferase levels, a sufficient course of treatment must be ensured. Experts point out that after enzyme-lowering drugs restore transaminase to normal, the dosage of enzyme-lowering drugs should be gradually reduced, and sudden discontinuation of the drugs should be avoided. After treatment of elevated aspartate aminotransferase, a certain period of consolidation treatment is required.

3. The treatment of elevated aspartate aminotransferase must be "two-pronged", "treating both the symptoms and the root cause". If you only use enzyme-lowering drugs, which only treat the symptoms but not the root cause, the aminotransferase can be temporarily controlled, but once the drugs are stopped, the aminotransferase tends to rise again. This "rebound" phenomenon is extremely common in clinical practice. In order to completely control the disease, antiviral treatment must be carried out first. Inhibiting and eliminating the hepatitis B virus is a fundamental measure. Simply protecting the liver and lowering enzymes is only a stopgap measure.

The increase of aspartate aminotransferase should attract our attention in time. Many of our lifestyles are unreasonable now, and many people are in sub-healthy state. In particular, more and more people have liver problems. If there are some abnormalities in the liver, everyone should go for examination and treatment in time. Severe liver disease is a threat to our life safety.