Symptoms of high alanine aminotransferase

Many institutions often hold free health educations. These free health educations penetrate into communities, villages, and fields, greatly improving the health awareness of the people. Many people know the importance of regular physical examinations, and they have developed a good habit of regular physical examinations. There are many physical examination items on the physical examination report, and alanine aminotransferase is an important one. What is alanine aminotransferase?

It is best if the alanine aminotransferase level is normal. A high alanine aminotransferase level means there is a problem with liver function, which is what we often call abnormal liver function. There are many reasons for elevated alanine aminotransferase, including liver cancer, cirrhosis, myocarditis, etc. The most common reason is hepatitis.

Symptoms of high alanine aminotransferase levels include insomnia, fatigue, poor appetite, low-grade fever, aversion to greasy food, jaundice, nausea, vomiting, abdominal pain, diarrhea, and discomfort in the liver area. Mild symptoms include sweating, drowsiness, thirst, and eye fatigue when reading.

Alanine aminotransferase is mainly present in the cytoplasm of liver cells, and its intracellular concentration is 1000-3000 times higher than that in serum. As long as 1% of liver cells are necrotic, serum enzymes can double. Therefore, alanine aminotransferase is recommended by the World Health Organization as the most sensitive detection indicator for liver function damage. But it is not organ-specific and many diseases can cause its increase. A significant increase is seen in acute viral hepatitis, a moderate increase is seen in chronic hepatitis, active cirrhosis, liver cancer, liver abscess, and a mild increase may also be seen in myocardial infarction, myocarditis, heart failure, etc. Therefore, the evaluation of elevated GPT should be closely integrated with clinical practice. Some increases in GPT are related to fatty liver and alcohol consumption. There are many liver-protecting drugs commonly used in clinical practice. However, some drugs may be effective but are prone to recurrence, causing some liver diseases to be incurable for a long time and a large number of liver cells to be damaged.

Once you have the above symptoms, you should pay great attention to it and go to a regular hospital for a physical examination in time to see if the alanine aminotransferase is elevated. If so, find out the cause and correct it in time. In daily life, everyone should not smoke, drink, and exercise more, so as to avoid alcoholic liver disease and fatty liver disease. The chance of alanine aminotransferase being normal is higher.