How to treat and recover from nerve edema

Neurogenic edema is also called acute neurovascular edema. It often causes localized skin or mucous membrane edema. Generally, patients do not experience itching and pain. There are many causes, mainly due to unstable nerve function. In addition, diet or drug allergies may also induce this condition. At this time, it must be treated in time. It can be treated by taking antihistamines.

Treatment

Antihistamine receptor H1 antagonists are often used for symptomatic treatment. For patients with stubborn disease that does not respond to antihistamine receptor antagonists, antihistamine receptor H2 antagonists such as cimetidine (cimetidine) or lantidine can be used in combination, which can sometimes achieve satisfactory results. Ketotifen can also be used in combination.

Sympathomimetic drugs are mainly used for patients with acute urticaria and/or neurogenic edema, especially laryngeal edema. 0.1% epinephrine should be injected subcutaneously. For severe acute allergic reactions, the injection can be repeated every 20 to 30 minutes. At the same time, glucocorticoids are given by intravenous drip and aminophylline is taken orally or injected intravenously. If the respiratory tract, especially the throat, edema occurs, tracheotomy or intubation should be performed if necessary to keep the airway open.

Attenuated androgens such as danazol, stanozolol (Stanozolol), oxymetholone (Anadrol), etc. can be used to treat congenital C1INH deficiency, correct its biochemical defects and prevent attacks, but they cannot be used in children and pregnant women. The latter can only be treated with anti-fibrinolytic drugs such as 6-aminocaproic acid, which can sometimes control spontaneous attacks.

Clinical manifestations

It is acute localized edema, which mostly occurs in loose tissue areas, such as eyelids, lips, foreskin and extremities, scalp, ears, oral mucosa, tongue, and throat. The affected skin is tight and shiny, with unclear boundaries, light red or pale in color, soft in texture, and non-pitting edema.

The patient feels no itching or mild itching, or has a numbness and swelling feeling. The swelling will subside after 2 to 3 days, or may last longer, leaving no trace after it subsides. It may occur singly or repeatedly in the same area, often accompanied by urticaria. When angioedema occurs in the laryngeal mucosa, there will be shortness of breath, discomfort in the throat, hoarseness, difficulty breathing, and even the possibility of suffocation. Generally there are no systemic symptoms.