How to treat high myocardial enzymes

Myocardial enzyme is a general term for other enzymes present in the myocardium. The level of myocardial enzyme is used in medicine to diagnose diseases such as myocardial infarction. It also has great value in medicine, but no matter how high or low the myocardial enzyme level is, it is abnormal and must be treated in time, otherwise it will cause other diseases. So how to treat high myocardial enzymes? Today I will tell you how to treat high myocardial enzymes.

What is the high myocardial enzyme that people often mention? What will be the impact if myocardial enzymes are found to be high? Is it serious?

Myocardial enzymes are a general term for a variety of enzymes present in the myocardium, generally including aspartate aminotransferase (AST), lactate dehydrogenase (LDH) and isoenzymes, α-hydroxybutyrate dehydrogenase (α-HBDH) and creatine kinase (CK) and isoenzymes (CKMB). In China, this group of enzymes related to myocardial damage are often collectively referred to as myocardial enzyme spectrum, which has certain value in diagnosing myocardial infarction.

The heart is one of the most active organs in the human body. In order to complete various physiological activities, there are a large number of cellular enzymes in the heart. After AMI occurs, myocardial ischemia and necrosis or increased cell membrane permeability causes the cellular enzymes in the myocardium to be released into the blood. Depending on the extent of myocardial damage, the extent of serum enzyme increase is also different. Therefore, changes in serum enzymes can be used to reflect the occurrence of AMI and the size of the lesion. At the same time, due to the different physiological characteristics of various enzymes, such as different localization in cells, different molecular weights, different biological half-lives, etc., the time for various enzymes to enter the blood, the speed of entry into the blood, and the duration in the serum are different, which provides a basis for clinical judgment of the course of disease and recovery.

What is high myocardial enzyme?

Myocardial enzymes: These enzymes increase to varying degrees after myocardial damage or necrosis. Among them, CK-MB and LDH1 have the highest specificity. Currently, the normal values ​​of myocardial enzyme spectrum are mostly based on adult standards, while the normal values ​​of children are higher than those of adults. Therefore, do not think that a child has myocarditis if his/her myocardial enzyme spectrum value increases. Since there are many factors that affect the myocardial enzyme spectrum, many hospitals use the measurement of cardiac troponin to assist in the diagnosis of myocarditis. The myocardial enzyme spectrum of most children is 2 to 3 times the normal reference value.

Examination of myocardial enzymes is mainly used to determine myocardial ischemia and necrosis or cell membrane permeability. High myocardial enzyme levels indicate myocardial damage, which is mostly caused by viral infection. It is recommended to have regular check-ups and get enough rest.

Myocardial enzyme spectrum reflects the degree of myocardial damage, but it is now gradually being phased out because the accuracy and sensitivity of this indicator are not as sensitive as myocardial injury markers such as myoglobin and troponin. Therefore, a high myocardial enzyme spectrum may be caused by myocardial ischemia, etc., and further investigation is needed.