Co-trimoxazole for the treatment of prostate

Co-trimoxazole is a drug that has a strong effect on some bacteria and fungi. In other words, some diseases caused by bacterial and fungal infections can still be treated with co-trimoxazole. Among prostate diseases, only some prostatitis caused by bacterial infection can be treated with co-trimoxazole. Let me introduce you to the relevant knowledge of co-trimoxazole in detail.

Drug Introduction

Co-trimoxazole is a sulfonamide antibiotic, a compound preparation of sulfamethoxazole (SMZ) and trimethoprim (TMP). It has good antibacterial effects on non-enzyme-producing Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, Escherichia coli, Klebsiella, Salmonella, Proteus, Morganella, Shigella and other Enterobacteriaceae, gonococci, Neisseria meningitidis and Haemophilus influenzae.

Indications

Since many common clinical pathogens are often resistant to this product, the drug sensitivity results must be referred to when treating bacterial infections. The main indications for this product are the following infections caused by sensitive strains.

Urinary tract infections caused by susceptible strains of Escherichia coli, Klebsiella, Enterobacter, Proteus mirabilis, Proteus vulgaris, and Morganella.

Acute otitis media in children over 2 years old caused by Streptococcus pneumoniae or Haemophilus influenzae.

Acute exacerbation of chronic bronchitis in adults caused by Streptococcus pneumoniae or Haemophilus influenzae.

Enteric infections and Shigella infections caused by susceptible strains of Shigella flexneri or sonnei.

This strain is the first choice for the treatment of Pneumocystis carinii pneumonia.

Prevention of Pneumocystis carinii pneumonia can be used in patients with a history of at least one attack of Pneumocystis carinii or in HIV-infected adults whose CD4 lymphocyte count is ≤200/mm3 or less than 20% of the total lymphocyte count.

Traveler's diarrhea caused by enterotoxigenic Escherichia coli (ETEC).

Precautions

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Crystalluria, hematuria, proteinuria, oliguria, low back pain, etc. are prone to occur. Patients with liver dysfunction should not use compound trimethoprim-sulfamethoxazole tablets.

Because it is difficult to eliminate bacteria, the following diseases should not be treated or prevented with this product

Prevention or long-term treatment of otitis media.

Group A hemolytic streptococcal tonsils and pharyngitis.

Cross allergic reaction. Patients who are allergic to one sulfonamide may also be allergic to other sulfonamides.

Liver damage. Jaundice and decreased liver function may occur, and in severe cases, acute liver necrosis may occur. Therefore, patients with liver damage should avoid its use.