Does taking urine stimulation mean that the ovarian follicles are not good?

For a woman to become pregnant, many aspects need to be normal, including a healthy uterus and healthy eggs. For a man, healthy sperm is also required. Only when all conditions are met can a successful pregnancy and childbirth occur. However, for some women, difficulty in ovulation can be solved by ovulation stimulation. But does urine stimulation mean that the ovulatory follicles are not good? This issue needs to be considered from multiple aspects.

Menotrophin is a postmenopausal gonadotropin. It mainly has the effect of follicle-stimulating hormone (FSH), while the effect of luteinizing hormone (LH) is very small. For women, it can promote the development and maturation of follicles, prompt the follicles to secrete estrogen, and cause endometrial hyperplasia. The subsequent addition of chorionic gonadotropin can enhance the ovulation-inducing effect. For men, it can promote the development of testicular seminiferous tubules, spermatogenic cell division and sperm maturation.

Indications

1. Used in combination with chorionic gonadotropin or clomiphene to treat anovulatory infertility. It can be used for patients with anovulation due to insufficient secretion of pituitary gonadotropin or hypothalamic gonadotropin-releasing hormone. It is currently generally recommended for use in cases where ovulation induction with clomiphene or bromocriptine is ineffective. When used in combination with clomiphene, the dosage of this product can be reduced by about 50% and the incidence of ovarian hyperstimulation can be reduced.

2. It is also used for primary or secondary amenorrhea, male sperm deficiency and ovarian function tests, etc.

Precautions

Because the rate of multiple pregnancy may be high, premature newborns are also more common. Common ovarian hyperstimulation syndrome, mild cases include fullness or pain in the stomach and pelvis, and mild enlargement of the ovaries, which disappears in 7 to 10 days. Moderate and severe cases may develop ascites and pleural effusion, and the ovaries may enlarge to 10 cm in diameter. The patient should be hospitalized to avoid irreversible electrolyte imbalance or even death. If symptoms such as abdominal pain, bloating, nausea, vomiting, and diarrhea occur during treatment, the medication should be stopped immediately. The use of this product often increases the risk of arterial embolism.

When women have abnormal follicular development but want to have children, they often need to take gonadotropin to promote the growth and discharge of follicles. After taking gonadotropin, there are often certain side effects. The most common side effect is that it will stimulate the development of multiple follicles at the same time, causing multiple pregnancies. It may also lead to excessive stimulation of the ovaries, causing distension and pain in the stomach and pelvis, and even nausea, vomiting, and diarrhea. It may also stimulate the ovaries to suddenly enlarge, leading to ovarian torsion or even ovarian rupture.