What is dwarfism?

In fact, we need to pay attention to scientific knowledge and understanding of dwarfism. Usually dwarfism is a disease caused by a genetic disease. Common manifestations are short stature and disproportionate bones. The occurrence of dwarfism is related to insufficient secretion of growth hormone, which causes physical retardation.

1. Dwarfism is a condition in which the body is delayed in development due to insufficient secretion of growth hormone caused by various reasons. The causes of dwarfism can be attributed to both congenital and acquired factors. Congenital factors are mostly caused by the deficiency of essence and blood of the parents, which affects the growth and development of the fetus. Most of them are related to genetics, and the intellectual development is generally normal.

2. Classification of Disease

1. Chondrodystrophy

It is a chromosomal dominant inheritance, mainly caused by the disorder of chondrocyte formation at the epiphyseal ends of long bones, which affects the length of bones and makes them thicker instead of growing. Children have short limbs but long trunk, so the length of the upper body is longer than the lower body. Hands do not hang above the hip joints, fingers are short and thick, and each finger is even. The nose bridge is low, the head circumference is large, the forehead and abdomen are protruding, the lumbar lordosis and the buttocks kyphosis are obvious, and the intelligence is normal. X-ray examination of long bones showed that the long bones were short, with increased curvature and bulging at both ends.

2 Congenital idiocy

Also known as Down syndrome, it is caused by autosomal abnormalities. The affected children are often short, with special facial features and intellectual disability. The children have low nose bridge, wide-set eyes, eyes that turn outward and upward, half-open mouths with tongues often sticking out of the mouths, continuous lines on the palms, short little fingers that bend inwards, and sometimes congenital heart disease. Chromosome analysis can confirm the diagnosis.

3 Mucopolysaccharidosis

It is caused by congenital mucopolysaccharide metabolism disorder, which causes excessive mucopolysaccharide storage in the cells of various tissues in the body. Normal at birth. Symptoms begin to appear between the ages of 6 months and 2 years. Children are short, have progressive mental retardation, and have skin problems.

The skin is rough and thick, the hair is dry, the eyes are wide apart, the nose is sunken, the tongue is large, and there is often hearing impairment, enlarged liver and spleen, a large and square head, and thick and short fingers. X-ray examination showed excessive ossification of bones throughout the body, enlarged sella turcica, premature closure of cranial sutures, and narrow proximal ends of the ribs and wide distal ends, shaped like a ribbon. The children's urine has increased mucopolysaccharides.