Medicines can often help us get rid of the troubles of diseases, but we cannot take all medicines we want. Instead, we must choose according to our actual situation. So, for people with poor gastrointestinal function and prone to constipation, it is necessary to clean the intestines in time. If we want to clean our intestines, what kind of medicine should we choose? You can choose the following medicines with confidence. 1. Bulk laxatives are used to relieve constipation. This type of drug works by changing the pH in the intestine, retaining water, and increasing stool volume, thereby stimulating colon peristalsis and keeping bowel movements smooth. In layman's terms, it makes the volume of stool expand and stimulates the peristalsis of the already somewhat paralyzed intestines to defecate. It is relatively safe in terms of mechanism. Lactulose and oligosaccharides sold on the market belong to this category. 2. Stimulant laxatives for bowel movements. This type of drug mainly stimulates the intestinal mucosa to increase intestinal motility and prevent intestinal fluid absorption, thereby playing a laxative role. For example, laxative tablets, senna leaves, and rhubarb are of this type. Because it is irritating, it is only suitable for temporary laxative purposes. If used for a long time, the intestines will continue to adapt to this stimulation, thus developing dependence. 3. Lubricating laxatives for bowel movements. It makes stool easier to pass by lubricating the intestines and softening the stool, such as paraffin and glycerin. Although glycerin can lubricate, it will increase the insulin content in the body and may interfere with blood sugar monitoring and treatment in diabetic patients. Therefore, this type of drug is mostly administered topically, such as enema. Local administration works faster and avoids absorption by the body. 4. Diphenylmethane drugs are used to treat constipation. Representative drugs include phenolphthalein, bisacodyl (bisacodyl), sodium picosulfate, etc. Phenolphthalein is the fruit laxative tablet that many constipation patients have taken. After oral administration, it meets the alkaline intestinal fluid in the intestine to form a soluble sodium salt, which can promote colon peristalsis. Soft stool will be discharged 6 to 8 hours after taking the medicine. It has a mild effect and is suitable for chronic constipation. Bisacodyl can be used for chronic constipation or for bowel cleansing before endoscopy or surgery. 5. Anthraquinone drugs have laxative effects. Representative medicines include rhubarb, senna leaves, cassia seed, aloe vera, cascara bark, and European cascara bark. After oral administration, these drugs are broken down into anthraquinones by bacteria in the large intestine. Because of the protection of sugar groups, most of them reach the large intestine directly without being absorbed, and are broken down into aglycones and sugars by bacterial enzymes in the intestine. Aglycones stimulate the large intestinal mucosa and inhibit the absorption of sodium ions from the intestinal cavity, which increases the water content in the large intestine, causes hyperperistalsis and leads to diarrhea. Defecation occurs 6 to 8 hours after taking the medicine. It is often used for acute and chronic constipation. |
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