How to treat corneal ulcer

Corneal ulcer is a common eye disease in clinical practice. The causes of this type of disease are generally complicated. When corneal ulcer occurs, it can cause great harm to people's bodies and directly affect people's lives and work. Therefore, timely treatment measures must be taken. How should corneal ulcers be treated? This is closely related to both the symptoms and the cause of the disease.

1. Lamellar transplantation

It is a partial-thickness corneal transplant. During surgery, the diseased tissue in front of the cornea is removed, leaving the underlying tissue as a transplant bed. The graft bed is usually very thin, with only the Descemet's membrane and endothelium remaining. Therefore, lamellar keratoplasty can be performed on patients whose corneal lesions have not invaded the deep layer of the corneal stroma or the Descemet's membrane and whose endothelial physiological function is healthy or recoverable. It is commonly used clinically for medium and shallow corneal leucoma or corneal dystrophic opacity, progressive keratitis or ulcer, corneal fistula, corneal tumor, and some eyes with poor conditions that cannot undergo penetrating keratoplasty. In order to improve the corneal condition, lamellar transplantation is performed first.

2. Penetrating transplantation

It is a method of replacing the entire layer of cloudy cornea with an entirely transparent cornea. Indications can be divided into optical, therapeutic, plastic, and cosmetic aspects according to their surgical purposes.

3. Prevention and treatment

In corneal ulcers, the exposed corneal stroma contains a large amount of collagen, and the biological glue can cross-link and bond with the collagen-rich tissue; at the same time, the fibronectin in the biological glue has the function of stimulating fibroblast proliferation, which can effectively stimulate ulcer healing and promote epithelial regeneration. According to clinical research, bio-glue is closer to the physiological healing process, has fewer new blood vessels, and can effectively close the cornea, effectively making up for the defect that the amniotic membrane cannot close the defect.